I also do stuff like eq/tape-saturation/compression/wow-flutter etc. on most of my samples beforehand.
Regarding my regular workflow on the Z I use it like below:
Tr1 - One shot drum kits containing a full kit (not only kick/snare/hi-hat/fx like you ‘should’ use it on the Z)
Tr2 - Sliced Drumloops
Tr3 - Multisampled instrument (synth/bass/piano/guitar etc.)
Tr4 - Multisampled instrument (synth/bass/piano/guitar etc.)
Tr5 - Bass samples
Tr6 - Melodic samples (pads and plucks)
Tr7 - Melodic samples (plucks and short notes)
Tr8 - Melodic samples (pads and long notes)
FX1 - Half wet or full wet delay with LFO on Pan for ping-pong effect
FX2 - Full wet reverb and bit of LFO on Pan or something else as well
Tape - Effecting chosen melodic content (most of the time Track 8) Fine on 100 (+12 semitones) or Fine on 0 (-12 Semitones) Filter on 30 with a bit of resonance and using a Full Dry signal. Tape track is going thru the full Wet reverb FX2 for a subtle and dark shimmer effect giving everything a more spacious feel
Master - Bit of Chorus (never above 30) and Drive on 50. Punch on 50 and Master around 50.
That’s about it! I am thinking about making a sound pack for the Z soon for the ones interested. The pack will contain most of the sounds of the above Z-Files album.